2025

• Fluorogenic Linkage Integration for Nonfluorescent Transformations (FLINT)
  Bishal Pokhrel, Fatiha Farhana, Li Zuo, Rebecca L Stratton, Pravin Pokhrel, Mohammad Akter Hossain, Jiahao Ji, Hanbin Mao, Hao Shen. Chemical & Biomedical Imaging, 2025, JUST PUBLISHED.

• Decoupling Activity and Specificity in Coronazymes
  Jiahao Ji, Li Zuo, Bishal Pokhrel, Pravin Pokhrel, Sajan Shakya, Hao Shen and Hanbin Mao. Small, 2025, 2500783.

  

• Logic-Gated Modulation of Cell Migration via Mesoscale Mechanical Uncaging Effects
  Deepak Karna, Shin Watanabe, Grinsun Sharma, Arpit Sharma, Yaorong Zheng, Ibuki Kawamata, Yuki Suzuki, Hanbin Mao. ACS Nano, 2025, 19, 8, 8058-8069.

  

2024

• De Novo Design of a Mechano-pharmaceutical Screening Platform against Nucleation of Individual Beta-Amyloid Oligomers
  Shankar Pandey,Mathias Bogetoft Danielsen, Yuan Xiang, Zhilei Zhang, Grinsun Sharma, Byeong Tak Jeon, Shixi Song, Yitong Hao, Gunan Zhang, Niels Johan Christensen, Kasper Kildegaard S�rensen, Pernille Harris, Pravin Pokhrel, Richard Cunningham, Min-Ho Kim, Yongsheng Leng, Chenguang Lou,* and Hanbin Mao*. Cell Reports Physical Science, 2024, 5, 12, 102336.

• Electroanalytical Quantification of DNA Chirality
  AKM Kafi, Pravin Pokhrel, Hao Shen, and Hanbin Mao*. Langmuir, 2024, 40, 47, 24968-24977.

  

• Modulation of dynamic DNA G-quadruplex structures in the hTERT promoter region by ligands
  Deepak Karna, Lin Liang, Grinsun Sharma, Shankar Mandal, Sefan Asamitsu, Yusuke Kawamoto, Kaori Hashiya, Toshikazu Bando, Hiroshi Sugiyama, and Hanbin Mao*. Nucleic Acids Research, 2024, 52, 10775�10787.

• Catalytic Relaxation of Kinetically Trapped Intermediates by DNA Chaperones
  Pravin Pokhrel, Deepak Karna, Sagun Jonchhe, and Hanbin Mao*. Journal of the American Chemical Society, 2024, 146, 19, 13046�13054.

  

• Dynamic Structures and Fast Transition Kinetics of Oxidized G-quadruplexes
  Jiahao Ji, Arpit Sharma, Pravin Pokhrel, Deepak Karna, Shankar Pandey, Yao-Rong Zheng*, and Hanbin Mao*. Small, 2024, 2400485.

2023

• Quality Research Follows the Power Law
  Hanbin Mao* and Jixin Chen*. Journal of Scientometric Research, 2023; 12(3): 570-576. DOI: 10.5530/jscires.12.3.054

• Peptide-DNA conjugates as building blocks for de novo design of hybrid nanostructures
  Mathias Bogetoft Danielsen, Hanbin Mao, Chenguang Lou*. Cell Reports Physical Science, 2023. DOI: 10.1016/j.xcrp.2023.101620

• Chemo-mechanical forces modulate the topology dynamics of mesoscale DNA assemblies
  Deepak Karna, Eriko Mano, Jiahao Ji, Ibuki Kawamata*, Yuki Suzuki*, and Hanbin Mao*. Nature communications, 2023, 55, 309-392.

  Check out the BEHIND THE PAPER from the authors!

  This article is also featured in a Nature Communications Editors' Highlights webpage.

• Methylene blue accelerates liquid-to-gel transition of tau condensates impacting tau function and pathology
  Yongqi Huang*, Wen Jitao, Lisa Marie Ramirez, Eymen Gümüsdil, Pravin Pokhrel, Haiqiong Ye, Yue Han, Yunfei Liu, Ping Li, Zhengding Su, Hanbin Mao, Markus Zweckstetter, Sarah Perrett, Si Wu, Meng Gao, Viet Man, and Junmei Wang. Nature communications, 2023, 14 (1), 5444.

• Single molecular dissection of liquid-liquid phase transitions
  Pravin Pokhrel, Sagun Jonchhe, Wei Pan, and Hanbin Mao*. Journal of the American Chemical Society, 2023, 145, 31, 17143-17150.

  

• Amalgamation of DNAzyme and Nanozyme in a Coronazyme
  Li Zuo, Kehao Ren, Xianing Guo, Pravin Pokhrel, Bishal Pokhrel, Mohammad Hossain, Chen Zhao-Xu, Hanbin Mao*, and Hao Shen*. Journal of the American Chemical Society, 2023, 145, 10, 5750 5758.

  This research has been featured in the cover page of the Journal of the American Chemical Society, Volume 145, March 15, 2023.

  

2022

• Ensemble Force Spectroscopy of a G-quadruplex Cluster on a Single-molecule Platform
  Pravin Pokhrel , Jiayi Wang , Sangeetha Selvam, Sagun Jonchhe, Shankar Mandal, Hanbin Mao*. Biomacromolecules, 2022, 23, 11, 4795 4803.

• Mechanical Stability of DNA Corona Phase on Gold Nanospheres
  Pravin Pokhrel, Kehao Ren, Hao Shen, Hanbin Mao*. Langmuir, 2022, 38, 44, 13569 13576.

• Zeptoliter DNA Origami Reactor to Reveal Cosolute Effects on Nanoconfined G-Quadruplexes
  Shankar Pandey, Sagun Jonchhe, Shubham Mishra, Tomoko Emura, Hiroshi Sugiyama, Masayuki Endo, and Hanbin Mao*. Journal of Physical Chemistry Letters, 2022, 13, 37, 8692 8698.

• Ensemble Force Spectroscopy by Shear Forces
  Pravin Pokhrel, Changpeng Hu, Hanbin Mao*. Journal of Visualized Experiments, 2022, DOI:10.3791/63741.

• Short LNA-modified oligonucleotide probes as efficient disruptors of DNA G-quadruplexes
  Souroprobho Chowdhury, Jiayi Wang, Sabrina Pia Nuccio, Hanbin Mao*, Marco Di Antonio*. Nucleic Acids Research, Volume 50, Issue 13, 22 July 2022, Pages 7247-7259.

• Single-molecule displacement assay reveals strong binding of polyvalent dendrimer ligands to telomeric G-quadruplex
  Pravin Pokhrel, Shogo Sasaki, Changpeng Hu, Deepak Karna, Shankar Pandey, Yue Ma, Kazuo Nagasawa*, Hanbin Mao*. Analytical Biochemistry, 2022, 114693.

• Single-Molecule Mechanochemical Sensing
  Changpeng Hu, Rabia Tahir, Hanbin Mao. Accounts of Chemical Research, 2022, 55, 9, 1214-1225.

• Small molecules modulate liquid-to-solid transitions in phase-separated Tau condensates
  Sagun Jonchhe, Wei Pan, Pravin Pokhrel, Hanbin Mao. Angewandte Chemie International Edition, DOI: 10.1002/anie.202113156

• Dissection of nanoconfinement and proximity effects on the binding events in DNA origami nanocavity
  Sagun Jonchhe, Shankar Pandey, Christian Beneze, Tomoko Emura, Hiroshi Sugiyama, Masayuki Endo, Hanbin Mao. Nucleic Acids Research, 2022, 50, 2, 697-703.

• Chirality transmission in macromolecular domains
  Shankar Pandey, Shankar Mandal, Mathias Bogetoft Danielsen, Asha Brown, Changpeng Hu, Niels Johan Christensen, Alina Vitaliyivna Kulakova, Shixi Song, Tom Brown, Knud J. Jensen, Jesper Wengel, Chenguang Lou, and Hanbin Mao. Nature Communications, 2022, 13, 76.

  This research has been reported in EurekAlert! news release 10-Jan-2022 Will this new superpower molecule revolutionize science?

Also highlighted in X-MOLNews 手性传递：一种全新的分子间作用力

And in ebiotrade.com 新型超级分子——将给科学带来革命！

2021

• Direct Measurement of Intermolecular Mechanical Force for Nonspecific Interactions between Small Molecules
  Shankar Pandey, Yuan Xiang, Dirk Friedrich, Yongsheng Leng, and Hanbin Mao*. The Journal of Physical Chemistry Letters, 2021, 12, 46, 11316-11322.

• Measurement of Single-Molecule Forces in Cholesterol and Cyclodextrin Host-Guest Complexes
  Shankar Pandey, Yuan Xiang, Dilanka V. D. Walpita Kankanamalage, Janarthanan Jayawickramarajah, Yongsheng Leng*, and Hanbin Mao*. The Journal of Physical Chemistry B, 2021, 125, 40, 11112-11121.

• DNA Origami Nanomechanics
  Jiahao Ji, Deepak Karna, and Hanbin Mao. Chemical Society Reviews, 2021,50, 11966-11978.

• Mechanical unfolding of ensemble biomolecular structures by shear force
  Changpeng Hu, Sagun Jonchhe, Pravin Pokhrel, Deepak Karna, Hanbin Mao. Chemical Science, 2021, 12, 10159-10164.

  

• Chemo-Mechanical Modulation of Cell Motions Using DNA Nanosprings
  Deepak Karna, Morgan Stilgenbauer, Sagun Jonchhe, Kazuya Ankai, Ibuki Kawamata, Yunxi Cui, Yao-Rong Zheng, Yuki Suzuki*, and Hanbin Mao*. Bioconjugate Chemistry, 2021, 2021, 32, 2, 311-317.

• Mechanochemical properties of DNA origami nanosprings revealed by force jumps in optical tweezers
  Deepak Karna, Wei Pan, Shankar Pandey, Yuki Suzuki, Hanbin Mao. Nanoscale, 2021, 2021, 13, 8425-8430.

2020

• Cooperative hetero-ligands interaction with G-quadruplexes shows evidence of allosteric binding
  Shankar Pandey, Yuanyuan Li, Montwaun Young, Shankar Mandal, Laichun Lu, Jacob Shelley, Hanbin Mao. Biochemistry, 2020, 59, 37, 3438-3446.

• Ensemble sensing using single-molecule DNA copolymers
  Sagun Jonchhe, Saneetha Selvam, Deepak Karna, Shankar Mandal, Benjamin Wales-McGrath, Hanbin Mao. Analytical Chemistry, 2020, 92,19, 13126-13133.

• A poly(thymine)-melamine duplex for the assembly of DNA nanomaterials
  Qian Li, Jiemin Zhao, Longfei Liu, Sagun Jonchhe, Felix J. Rizzuto, Shankar Mandal, Huawei He, Sansen Wei, Hanadi F. Sleiman*, Hanbin Mao* & Chengde Mao*. Nature Materials, 2020, 19, 1012-1018.

  This research has been highlighted in Chemistry and Engineering News (C&EN), 2020 as Melamine mediates formation of polythymine duplexes.

It has been recommended by Professor Francesco Ricci at F1000 faculty website as A poly(thymine)-melamine duplex for the assembly of DNA nanomaterials.

It is also highlighted in Cailiaoniu.com as Purdue & Kent State & McGill Nat. Mater.: A new breakthrough in the artificial construction of double-stranded DNA!

And in Nanoer.com as Nature Materials：聚胸腺嘧啶-三聚氰胺双链体用于组装DNA纳米材料 (Chinese).

• Duplex DNA is Weakened in Nanoconfinement
  Sagun Jonchhe, Shankar Pandey, Deepak Karna, Pravin Pokhrel, Shubham Mishra, Hiroshi Sugiyama, Masayuki Endo, Hanbin Mao. Journal of the American Chemical Society, 2020, 142, 22, 10042-10049.

• Detecting the Coronavirus (COVID-19)
  Pravin Pokhrel, Changpeng Hu, Hanbin Mao. ACS Sensors, 2020, 5, 2283-2296.

  This review has been listed as the Journal's Most Read Article in the past 30 days as well as in the past 12 months. Click here to see the details.

  For a free and a little earlier, shortened pdf version, please see our Preprint.

• Chiral Interaction Is a Decisive Factor To Replace D-DNA with L-DNA Aptamers
  Xuenan Feng, Yunxi Cui, Jin Zhang, Anna Tang, Hanbin Mao, Deming Kong Analytical Chemistry, 2020,92, 9, 6470-6477.

2019

• Chaperone Assisted Host-Guest Interactions Revealed by Single-Molecule Force Spectroscopy
  Shankar Pandey, Dilanka Kankanamalage, Xiao Zhou, Changpeng Hu, Lyle Isaacs, Janarthanan Jayawickramarajah, Hanbin Mao Journal of the American Chemical Society, 2019, 141, 46, 18385-18389.

• Single-Molecule Topochemical Analyses for Large-Scale Multiplexing Tasks
  Shankar Mandal, Xiaoqing Zhang, Shankar Pandey, Hanbin Mao. Analytical Chemistry, 2019, 91, 21, 13485-13493.

• Submolecular dissection reveals strong and specific binding of polyamide-pyridostatin conjugates to human telomere interface
  Shankar Mandal, Yusuke Kawamoto, Zhizhou Yue, Kaori Hashiya, Yunxi Cui, Toshikazu Bando, Shankar Pandey, Mohammaed Enamul Hoque, Mohammed Akter Hossain, Hiroshi Sugiyama, Hanbin Mao. Nucleic Acids Research, 2019,47, 7, 3295-3305.

• Binding of a Telomestatin Derivative Changes Mechanical Anisotropy of Human Telomeric G-quadruplex
  Sagun Jonchhe, Chiran Ghimire, Yunxi Cui, Shogo Sasaki, Mason McCool, Soyoung Park, Keisuke Iida, Kazuo Nagasawa, Hiroshi Sugiyama, Hanbin Mao. Angewandte Chemie International Edition, 2019, 58, 877-881.

• Single-Molecule Investigations of G-Quadruplex
  Shankar Mandal, Mohammed Enamul Hoque, Hanbin Mao. G-Quadruplex Nucleic Acids, Springer, 2019. [Book Chapter]

• Single-Molecule Mechanochemical Sensing Using DNA Origami Nanostructures
  Sagun Jonchhe, Hanbin mao. Biomimetic Sensing, Springer, 2019. [Book Chapter]

2018

• Random Formation of G-Quadruplexes in the Full-Length Human Telomere Overhangs Leads to a Kinetic Folding Pattern with Targetable Vacant G-Tracts
  Jibin Abraham Punnoose, Yue Ma, Mohammed Enamul Hoque, Yunxi Cui, Shogo Sasaki, Athena Huixin Guo, Kazuo Nagasawa, Hanbin Mao. Biochemistry, 2018, 57, 51, 6946-6955

• Mechanical Cooperativity in DNA Cruciform Structures
  Shankar Mandal, Sangeetha Selvam, Yunxi Cui, Mohammed Enamul Hoque, Hanbin Mao. ChemPhysChem, 2018, 19, 2627-2634

  This research has been highlighted as a cover story in the journal.

  

• Decreased water activity in nanoconfinement contributes to the folding of G-quadruplex and i-motif structures
  Sagun Jonchhe, Shankar Pandey, Tomoko Emura, Kumi Hidaka, Mohammad Akter Hossain, Prakash Shrestha, Hiroshi Sugiyama, Masayuki Endo, Hanbin Mao. Proceedings of the National Academy of Sciences, 2018, 115, 38, 9539-9544.

• Single-Molecule Mechanochemical pH Sensing Revealing the Proximity Effect of Hydroniums Generated by an Alkaline Phosphatase
  Prakash Shrestha, Yunxi Cui, Jia Wei, Sagun Jonchhe, Hanbin Mao. Analytical Chemistry, 2018, 90, 3, 1718-1724.

• A New Concentration Jump Strategy Reveals the Lifetime of i-Motif at Physiological pH without Force
  Sagun Jonchhe, Prakash Shrestha, Katia Ascencio, Hanbin Mao. Analytical Chemistry, 2018, 90, 5, 3205-3210.

2017

• Quantification of Chemical and Mechanical Effects on the Formation of the G-Quadruplex and i-Motif in Duplex DNA
  Sangeetha Selvam, Shankar Mandal, Hanbin Mao. Biochemistry, 2017, 56, 35, 4616-4625.

  

This research has been highlighted as a cover story in the journal.

• Adaptive and Specific Recognition of Telomeric G-Quadruplexes via Polyvalency Induced Unstacking of Binding Units
  Jibin Abraham Punnoose, Yue Ma, Yuanyuan Li, Mai Sakuma, Shankar Mandal, Kazuo Nagasawa, Hanbin Mao. Journal of the American Chemical Society, 2017, 139, 22, 7476-7484.

• Confined space facilitates G-quadruplex formation
  Prakash Shrestha, Sagun Jonchhe, Tomoko Emura, Kumi Hidaka, Masayuki Endo, Hiroshi Sugiyama, Hanbin Mao . Nature Nanotechnology, 2017, 12, 582-588.

This research has been highlighted in Science Daily as Chemists create microscopic environment to study cancer cell growth.

This research has been highlighted in Eurekalert as Nanocages dramatically facilitate structure formation of biomolecules.

2016

• A Mechanosensor Mechanism Controls the G-Quadruplex/i-Motif Molecular Switch in the MYC Promoter NHE III1
  Caleb Sutherl, Yunxi Cui, Hanbin Mao, Laurence H. Hurley. Journal of the American Chemical Society, 2016, 138, 42, 14138-14151.

• A Pharmacological Chaperone Molecule Induces Cancer Cell Death by Restoring Tertiary DNA Structures in Mutant hTERT Promoters
  Hyun-Jin Kang, Yunxi Cui, Holly Yin, Amy Scheid, William P. D. Hendricks, Jessica Schmidt, Aleksandar Sekulic, Deming Kong, Jeffrey M. Trent, Vijay Gokhale, Hanbin Mao, Laurence H. Hurley. Journal of the American Chemical Society, 2016, 138, 41, 13673-13692.

• Mechanochemical Sensing of Single and Few Hg(II) Ions Using Polyvalent Principles
  Shankar Mandal, Sangeetha Selvam, Prakash Shrestha, Hanbin Mao. Analytical Chemistry, 2016, 88, 19, 9479-9485.

• Mechanical properties of DNA origami nanoassemblies are determined by Holliday junction mechanophores
  Prakash Shrestha, Tomoko Emura, Deepak Koirala, Yunxi Cui, Kumi Hidaka, William J Maximuck, Masayuki Endo, Hiroshi Sugiyama, Hanbin Mao. Nucleic Acids Research, 2016, 44, 14, 6574-6582.

• Mutually Exclusive Formation of G-Quadruplex and i-Motif Is a General Phenomenon Governed by Steric Hindrance in Duplex DNA
  Yunxi Cui, Deming Kong, Chiran Ghimire, Cuixia Xu, Hanbin Mao. Biochemistry, 2016,55, 15, 2291-2299.

• Exploded view of higher order G-quadruplex structures through click-chemistry assisted single-molecule mechanical unfolding
  Sangeetha Selvam, Zhongbo Yu, Hanbin Mao. Nucleic Acids Research, 2016, 44, 1, 45-55.

2015

• A Molecular Tuning Fork in Single‐Molecule Mechanochemical Sensing
  Shankar Mandal, Deepak Koirala, Sangeetha Selvam, Chiran Ghimire, Hanbin Mao. Angewandte Chemie International Edition, 2015, 127, 7717-7721.

• Mechanochemical Sensing: A Biomimetic Sensing Strategy
  Prakash Shrestha, Shankar Mandal, Hanbin Mao. ChemPhysChem, 2015, 16, 1829-1837.

• Dissecting Cooperative Communications in a Protein with a High‐Throughput Single‐Molecule Scalpel
  Zhongbo Yu, Yunxi Cui, Sangeetha Selvam, Chiran Ghimire, Hanbin Mao. ChemPhysChem, 2015, 16, 223-232.

• Dual Binding of an Antibody and a Small Molecule Increases the Stability of TERRA G‐Quadruplex
  Philip M. Yangyuoru, Marco Di Antonio, Chiran Ghimire, Giulia Biffi, Shankar Balasubramanian, Hanbin Mao. Angewandte Chemie International Edition, 2015, 54, 910-913.

• Mechanochemical Sensing
  Prakash Shrestha, Shankar Mandal, Hanbin Mao. RNA and DNA Diagnostics, Springer, 2015. [Book Chapter]

2014

• Interaction of G-quadruplexes in the Full-length 3' Human Telomeric Overhang
  Jibin Abraham Punnoose, Yunxi Cui, Deepak Koirala, Philip M. Yangyuoru, Chiran Ghimire, Prakash Shrestha, and Hanbin Mao. Journal of the American Chemical Society, 2014, 136, 52, 18062-18069.

• Direct Quantification of Loop Interaction and π-π Stacking for G-Quadruplex Stability at the Submolecular Level
  Chiran Ghimire, Soyoung Park, Keisuke Iida, Philip Yangyuoru, Haruka Otomo, Zhongbo Yu, Kazuo Nagasawa, Hiroshi Sugiyama, and Hanbin Mao. Journal of the American Chemical Society, 2014, 136, 44, 15537-15544.

• Quantification of Topological Coupling between DNA Superhelicity and G-quadruplex Formation
  Sangeetha Selvam, Deepak Koirala, Zhongbo Yu, and Hanbin Mao. Journal of the American Chemical Society, 2014, 136, 40, 13967-13970.

• Intermediates Stabilized by Tryptophan Pairs Exist in Trpzip Beta-Hairpins
  Zhongbo Yu, Sangeetha Selvam, and Hanbin Mao. Biochemistry, 2014, 53, 38, 5978-5986.

• Single-Molecule Mechanochemical Sensing Using DNA Origami Nanostructures
  Deepak Koirala, Prakash Shrestha, Tomoko Emura, Kumi Hidaka, Shankar Mandal, Masayuki Endo, Hiroshi Sugiyama, Hanbin Mao. Angewandte Chemie International Edition , 2014, 126, 8275-8279.

  This research has been highlighted as a cover story in the journal.

  

• Nascent RNA transcripts facilitate the formation of G-quadruplexes
  Prakash Shrestha, Shan Xiao, Soma Dhakal, Zheng Tan, Hanbin Mao. Nucleic Acids Research, 2014, 42, 11, 7236-7246.

• Molecular population dynamics of DNA structures in a bcl-2 promoter sequence is regulated by small molecules and the transcription factor hnRNP LL
  Yunxi Cui, Deepak Koirala, HyunJin Kang, Soma Dhakal, Philip Yangyuoru, Laurence H. Hurley, Hanbin Mao. Nucleic Acids Research, 2014, 42, 9, 5755-5764.

This research has been highlighted in Chemistry and Engineering News (C&EN), 2014 as Role Of Mysterious Folded DNA Structures Revealed At Last.

• Yoctoliter Thermometry for Single-Molecule Investigations: A Generic Bead-on-a-Tip Temperature-Control Module
  Deepak Koirala, Jibin Abraham Punnoose, Prakash Shrestha, Hanbin Mao. Angewandte Chemie International Edition, 2014, 53, 3470-3474.

  This research has been highlighted as a cover story in the journal.

  This research has been highlighted in Nature Nanotechnology as A controlled jump.

  

• Controlled Particle Collision Leads to Direct Observation of Docking and Fusion of Lipid Droplets in an Optical Trap
  Chiran Ghimire, Deepak Koirala, Malcom B. Mathis, Edgar E. Kooijman, Hanbin Mao. Langmuir, 2014, 30, 5, 1370-1375.

2013

• Mechanochemical Properties of Individual Human Telomeric RNA (TERRA) G-Quadruplexes
  Philip M. Yangyuoru , Amy Y. Q. Zhang, Zhe Shi, Deepak Koirala, Shankar Balasubramanian, Hanbin Mao. ChemBioChem, 2013, 14, 15, 1931-1935.

• Mechanical affinity as a new metrics to evaluate binding events
  Deepak Koirala, Philip M. Yangyuoru, Hanbin Mao. Reviews in Analytical Chemistry, 2013, 32, 3, 197-208.

• Structural and mechanical properties of individual human telomeric G-quadruplexes in molecularly crowded solutions
  Soma Dhakal, Yunxi Cui, Deepak Koirala, Chiran Ghimire, Saurabh Kushwaha, Zhongbo Yu, Philip M. Yangyuoru, Hanbin Mao. Nucleic Acids Research, 2013, 41, 6, 3915-3923.

• Long-Loop G-Quadruplexes Are Misfolded Population Minorities with Fast Transition Kinetics in Human Telomeric Sequences
  Deepak Koirala, Chiran Ghimire, Christopher Bohrer, Yuta Sannohe, Hiroshi Sugiyama, Hanbin Mao. Journal of the American Chemical Society, 2013, 135, 6, 2235-2241.

• Non-B DNA Structures Show Diverse Conformations and Complex Transition Kinetics Comparable to RNA or Proteins-A Perspective from Mechanical Unfolding and Refolding Experiments
  Zhongbo Yu, Hanbin Mao. The Chemical Record, 2013, 13, 102-116.

2012

• G-quadruplex Nanostructures Probed at the Single Molecular Level by Force-based Methods
  Soma Dhakal, Hanbin Mao, Arivazhagan Rajendran, Masayuki Endo and Hiroshi Sugiyama. Guanine Quartets: Structure and Application, 2012. [Book Chapter]

• Click Chemistry Assisted Single-Molecule Fingerprinting Reveals a 3D Biomolecular Folding Funnel
  Zhongbo Yu, Deepak Koirala, Yunxi Cui, Leah F. Easterling, Yuan Zhao, Hanbin Mao. Journal of the American Chemical Society, 2012, 134, 30, 12338-12341.

• Intramolecular Folding in Human ILPR Fragment with Three C-Rich Repeats
  Soma Dhakal, Javonne L. Lafontaine, Zhongbo Yu, Deepak Koirala, Hanbin Mao. PLOS ONE, 2012, 7, 6, e39271.

• G-Quadruplex and i-Motif Are Mutually Exclusive in ILPR Double-Stranded DNA
  Soma Dhakal, Zhongbo Yu, Ryan Konik, Yunxi Cui, Deepak Koirala, Hanbin Mao. Biophysical Journal, 2012, 102, 2575-2584.

• Single-Molecule Measurements of the Binding between small Molecules and DNA Aptamers
  Philip M. Yangyuoru, Soma Dhakal, Zhongbo Yu, Deepak Koirala, Simon M. Mwongela, Hanbin Mao. Analytical Chemistry, 2012,84, 12, 5298-5303.

• Tertiary DNA Structure in the Single-Stranded hTERT Promoter Fragment Unfolds and Refolds by Parallel Pathways via Cooperative or Sequential Events
  Zhongbo Yu, Vanessa Gaerig, Yunxi Cui, HyunJin Kang, Vijay Gokhale, Yuan Zhao, Laurence H. Hurley, Hanbin Mao. Journal of the American Chemical Society, 2012, 134, 11, 5157-5164.

• Intramolecular folding in three tandem guanine repeats of human telomeric DNA
  Deepak Koirala, Tomoko Mashimo, Yuta Sannohe, Zhongbo Yu, Hanbin Mao, Hiroshi Sugiyama. Chemical Communications, 2012,. 48, 2006-2008.

2011

• Detection of Single Nucleotide Polymorphism Using Tension-Dependent Stochastic Behavior of a Single-Molecule Template
  Deepak Koirala, Zhongbo Yu, Soma Dhakal, Hanbin Mao. Journal of the American Chemical Society, 2011, 133, 26, 9988-9991.

• A single-molecule platform for investigation of interactions between G-quadruplexes and small-molecule ligands
  Deepak Koirala, Soma Dhakal, Beth Ashbridge, Yuta Sannohe, Raphael Rodriguez, Hiroshi Sugiyama, Shankar Balasubramanian, Hanbin Mao. Nature Chemistry, 2011, 3, 782-787.

This paper has been highlighted in News and Views in Nature Chemistry: Untying a nanoscale knot





2010




• Coexistence of an ILPR i-Motif and a Partially Folded Structure with Comparable Mechanical Stability Revealed at the Single-Molecule Level
  Soma Dhakal, Joseph D. Schonhoft, Deepak Koirala, Zhongbo Yu, Soumitra Basu, Hanbin Mao. Journal of the American Chemical Society, 2010, 132, 26, 8991-8997.

• ILPR repeats adopt diverse G-Quadruplex conformations that determine insulin binding
  Joseph D. Schonhoft, Arijit Das, Firehiwot Achamyeleh, Sheema Samdani, Abby Sewell, Hanbin Mao, Soumitra Basu. Biopolymers, 2010, 93,1,21-31.

2009




• ILPR G-Quadruplexes Formed in Seconds Demonstrate High Mechanical Stabilities
  Zhongbo Yu, Joseph D. Schonhoft, Soma Dhakal, Rabindra Bajracharya, Ravi Hegde, Soumitra Basu, Hanbin Mao. Journal of the American Chemical Society, 2009,131, 5, 1876-1882.

This research has also been recommended by Professor Stephen Neidle at F1000 faculty website as ILPR G-quadruplexes formed in seconds demonstrate high mechanical stabilities.

• Direct experimental evidence for quadruplex-quadruplex interaction within the human ILPR
  Joseph D. Schonhoft, Rabindra Bajracharya, Soma Dhakal, Zhongbo Yu, Hanbin Mao, Soumitra Basu. Nucleic Acids Research, 2009, 37, 10, 3310-3320.

For more articles, please visit Google Scholar